Our Members
Denisa D. Wagner, PhD - Principal Investigator
Dr. Wagner received her Diploma of Biochemistry from the Universite de Geneve, Switzerland and PhD in Biology from the Massachusetts Institute of Technology. She served on the faculty at the University of Rochester, NY and Tufts University School of Medicine before coming to Harvard Medical School in 1994. Dr. Wagner is currently the Edwin Cohn Professor of Pediatrics in the Program for Cellular and Molecular Medicine and the Division of Hematology/Oncology at Boston Children's Hospital.
E-mail: denisa.wagner@childrens.harvard.edu
Dr. Wagner received her Diploma of Biochemistry from the Universite de Geneve, Switzerland and PhD in Biology from the Massachusetts Institute of Technology. She served on the faculty at the University of Rochester, NY and Tufts University School of Medicine before coming to Harvard Medical School in 1994. Dr. Wagner is currently the Edwin Cohn Professor of Pediatrics in the Program for Cellular and Molecular Medicine and the Division of Hematology/Oncology at Boston Children's Hospital.
E-mail: denisa.wagner@childrens.harvard.edu
Tiffany Frary, BA - Senior Administrative Associate
Started in the Wagner Lab in October 2018
Previous Placements
University of Vermont, Burlington, VT, USA - BA in English, minor in Human Development
Before joining the lab, Tiffany worked as an editor, publisher, and new series developer with Arcadia Publishing.
E-mail: tiffany.frary@childrens.harvard.edu
Started in the Wagner Lab in October 2018
Previous Placements
University of Vermont, Burlington, VT, USA - BA in English, minor in Human Development
Before joining the lab, Tiffany worked as an editor, publisher, and new series developer with Arcadia Publishing.
E-mail: tiffany.frary@childrens.harvard.edu
Long H. Chu, BS - Lab Manager
Started in the Wagner Lab in July 2016
Previous Research
This is Long's first posting in a research position in a lab. Before becoming the lab manager, Long was a research assistant in the Wagner Lab.
Previous Placements
UMass Lowell, Lowell, MA, USA - BS in Molecular Biology
Eton Bioscience Inc. - Specializing in DNA Sequencing
E-mail: long.chu@childrens.harvard.edu
Started in the Wagner Lab in July 2016
Previous Research
This is Long's first posting in a research position in a lab. Before becoming the lab manager, Long was a research assistant in the Wagner Lab.
Previous Placements
UMass Lowell, Lowell, MA, USA - BS in Molecular Biology
Eton Bioscience Inc. - Specializing in DNA Sequencing
E-mail: long.chu@childrens.harvard.edu
Patrick Münzer, PhD - Postdoctoral Fellow
Started in the Wagner Lab in October 2017
Previous Research
Patrick's previous work focused on the molecular basis of hemostasis and pathological thrombosis with subsequent thrombo-occlusive events leading to myocardial infarction and ischemic stroke. He investigated the role of the Phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) pathway and associated kinases in platelet signaling and activation.
Previous Placements
The University of Freiburg, Germany - BS in Biology
The University of Tübingen, Germany - PhD in Physiology
Under the supervision of Prof. Florian Lang, MD
The University Hospital of Tübingen, Germany - Postdoctoral Research Fellow in Thrombosis/Hemostasis
Under the supervision of Prof. Meinrad Gawaz, MD
E-mail: patrick.muenzer@childrens.harvard.edu
Started in the Wagner Lab in October 2017
Previous Research
Patrick's previous work focused on the molecular basis of hemostasis and pathological thrombosis with subsequent thrombo-occlusive events leading to myocardial infarction and ischemic stroke. He investigated the role of the Phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) pathway and associated kinases in platelet signaling and activation.
Previous Placements
The University of Freiburg, Germany - BS in Biology
The University of Tübingen, Germany - PhD in Physiology
Under the supervision of Prof. Florian Lang, MD
The University Hospital of Tübingen, Germany - Postdoctoral Research Fellow in Thrombosis/Hemostasis
Under the supervision of Prof. Meinrad Gawaz, MD
E-mail: patrick.muenzer@childrens.harvard.edu
Shoichi Fukui, MD, PhD - Postdoctoral Fellow
Started in the Wagner lab in June 2018
Shoichi came to the Wagner lab from Japan to study the relationship between neutrophil extracellular traps (NETs) and rheumatoid arthritis.
Previous Research
Shoichi studied subsets of monocytes and osteoclasts in rheumatoid arthritis using human peripheral blood samples. He also researched vasculitis and complement pathways clinically.
Previous Placements
Nagasaki University, Nagasaki, Japan - MD
Nagasaki University, Nagasaki, Japan - PhD in Medicine
Immunology and Rheumatology, Prof. Atsushi Kawakami
Post-doctoral Career
Assistant Professor, Department of Community Medicine, Nagasaki University, Nagasaki, Japan
E-mail: shoichi.fukui@childrens.harvard.edu
Started in the Wagner lab in June 2018
Shoichi came to the Wagner lab from Japan to study the relationship between neutrophil extracellular traps (NETs) and rheumatoid arthritis.
Previous Research
Shoichi studied subsets of monocytes and osteoclasts in rheumatoid arthritis using human peripheral blood samples. He also researched vasculitis and complement pathways clinically.
Previous Placements
Nagasaki University, Nagasaki, Japan - MD
Nagasaki University, Nagasaki, Japan - PhD in Medicine
Immunology and Rheumatology, Prof. Atsushi Kawakami
Post-doctoral Career
Assistant Professor, Department of Community Medicine, Nagasaki University, Nagasaki, Japan
E-mail: shoichi.fukui@childrens.harvard.edu
Karen Aymonnier, PhD - Postdoctoral Fellow
Started in the Wagner Lab in August 2019
Previous Research
Karen's previous work focused on Protease Nexin-1 (PN-1) as a promising target in hemophilia treatment. She also investigated PN-1 role in neutrophil functions.
Previous Placements
The University of Paris Sorbonne, France - PhD in Hematology
Under the supervision of Dr. Marie-Christine Bouton
The University of Paris Sorbonne, France - MS in Physiology
Under the supervision of Dr. Marie-Christine Bouton
The University of Complutense de Madrid, Spain - MS in Physiology
Under the supervision of Prof. Elena Vara
E-mail: karen.aymonnier@childrens.harvard.edu
Started in the Wagner Lab in August 2019
Previous Research
Karen's previous work focused on Protease Nexin-1 (PN-1) as a promising target in hemophilia treatment. She also investigated PN-1 role in neutrophil functions.
Previous Placements
The University of Paris Sorbonne, France - PhD in Hematology
Under the supervision of Dr. Marie-Christine Bouton
The University of Paris Sorbonne, France - MS in Physiology
Under the supervision of Dr. Marie-Christine Bouton
The University of Complutense de Madrid, Spain - MS in Physiology
Under the supervision of Prof. Elena Vara
E-mail: karen.aymonnier@childrens.harvard.edu
Lai Shi, PhD - Postdoctoral Fellow
Started in the Wagner Lab in August 2019
Previous Research
Lai's previous work showed that elevated PAD4 activity can elicit the formation of extracellular chromatin network from 4T1 cancer cells themselves. He termed this chromatin structure Cancer Extracellular Chromatin Network (CECN) to reflect the cancer cell origin of these extracellular chromatin structures. Moreover, using CRISPR/Cas9 cell lines and PAD4 knockout mice as tools, he showed that PAD4 is an essential lung metastasisregulator of breast cancer 4T1 cells.
Previous Placements
Institute of Zoology, Chinese Academy of Sciences, China - MS in Cell Biology
The Pennsylvania State University, USA - PhD in Molecular, Cellular, and Integrative Bioscience
Under the supervision of Prof. Yanming Wang, PhD
E-mail: lai.shi@childrens.harvard.edu
Started in the Wagner Lab in August 2019
Previous Research
Lai's previous work showed that elevated PAD4 activity can elicit the formation of extracellular chromatin network from 4T1 cancer cells themselves. He termed this chromatin structure Cancer Extracellular Chromatin Network (CECN) to reflect the cancer cell origin of these extracellular chromatin structures. Moreover, using CRISPR/Cas9 cell lines and PAD4 knockout mice as tools, he showed that PAD4 is an essential lung metastasisregulator of breast cancer 4T1 cells.
Previous Placements
Institute of Zoology, Chinese Academy of Sciences, China - MS in Cell Biology
The Pennsylvania State University, USA - PhD in Molecular, Cellular, and Integrative Bioscience
Under the supervision of Prof. Yanming Wang, PhD
E-mail: lai.shi@childrens.harvard.edu
Jean-Philippe Desilles - Postdoctoral Fellow
Started in the Wagner Lab in November 2019
Jean-Philippe came to the Wagner lab from France to study the relationship between neutrophil extracellular traps (NETs) and acute ischemic stroke.
Previous Research
Jean-Philippe's previous work focused on downstream microvascular responses to cerebral ischemia/reperfusion with particular respect to blood flow, thromboinflammation, and blood-brain barrier damage.
Previous Placements
University of Paris Diderot, Paris, France - PhD in Biology
Under the supervision of Prof. Mikael Mazighi, MD, PhD and Dr Benoit Ho-Tin-Noé, PhD
University of Lyon 1, Lyon, France – MD in Neurology
E-mail: jean-philippe.desilles@childrens.harvard.edu
Post-doctoral Career
Assistant Professor, Department of Interventional Neuroradiology, University of Paris, Rothschild Foundation Hospital, Paris, France
Started in the Wagner Lab in November 2019
Jean-Philippe came to the Wagner lab from France to study the relationship between neutrophil extracellular traps (NETs) and acute ischemic stroke.
Previous Research
Jean-Philippe's previous work focused on downstream microvascular responses to cerebral ischemia/reperfusion with particular respect to blood flow, thromboinflammation, and blood-brain barrier damage.
Previous Placements
University of Paris Diderot, Paris, France - PhD in Biology
Under the supervision of Prof. Mikael Mazighi, MD, PhD and Dr Benoit Ho-Tin-Noé, PhD
University of Lyon 1, Lyon, France – MD in Neurology
E-mail: jean-philippe.desilles@childrens.harvard.edu
Post-doctoral Career
Assistant Professor, Department of Interventional Neuroradiology, University of Paris, Rothschild Foundation Hospital, Paris, France
Saeko Fukui, MD - Research Assistant II
Started in the Wagner Lab in February 2019
Previous Research
This is Saeko's first posting in a research position in a lab.
Previous Placements
Nagasaki University, Nagasaki, Japan - MD
Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Medical staff in the Department of Surgery, Prof. Susumu Eguchi
E-mail: saeko.fukui@childrens.harvard.edu
Started in the Wagner Lab in February 2019
Previous Research
This is Saeko's first posting in a research position in a lab.
Previous Placements
Nagasaki University, Nagasaki, Japan - MD
Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Medical staff in the Department of Surgery, Prof. Susumu Eguchi
E-mail: saeko.fukui@childrens.harvard.edu
Sarah Gutch - Research Assistant
Started in the Wagner Lab in July 2019
Previous Research
This is Sarah's first posting in a research position in a lab.
Previous Placements
Bates College, Lewiston, ME, USA - BS in Biology
E-mail: sarah.gutch@childrens.harvard.edu
Started in the Wagner Lab in July 2019
Previous Research
This is Sarah's first posting in a research position in a lab.
Previous Placements
Bates College, Lewiston, ME, USA - BS in Biology
E-mail: sarah.gutch@childrens.harvard.edu