Our Members
Denisa D. Wagner, PhD - Principal Investigator
Dr. Wagner received her Diploma of Biochemistry from the Universite de Geneve, Switzerland and PhD in Biology from the Massachusetts Institute of Technology. She served on the faculty at the University of Rochester, NY and Tufts University School of Medicine before coming to Harvard Medical School in 1994. Dr. Wagner is currently the Edwin Cohn Professor of Pediatrics in the Program for Cellular and Molecular Medicine and the Division of Hematology/Oncology at Boston Children's Hospital.
E-mail: denisa.wagner@childrens.harvard.edu
Dr. Wagner received her Diploma of Biochemistry from the Universite de Geneve, Switzerland and PhD in Biology from the Massachusetts Institute of Technology. She served on the faculty at the University of Rochester, NY and Tufts University School of Medicine before coming to Harvard Medical School in 1994. Dr. Wagner is currently the Edwin Cohn Professor of Pediatrics in the Program for Cellular and Molecular Medicine and the Division of Hematology/Oncology at Boston Children's Hospital.
E-mail: denisa.wagner@childrens.harvard.edu
Tiffany Frary, BA - Senior Administrative Associate
Started in the Wagner Lab in October 2018
Previous Placements
University of Vermont, Burlington, VT, USA - BA in English, minor in Human Development
Before joining the lab, Tiffany worked as an editor, publisher, and new series developer with Arcadia Publishing.
E-mail: tiffany.frary@childrens.harvard.edu
Started in the Wagner Lab in October 2018
Previous Placements
University of Vermont, Burlington, VT, USA - BA in English, minor in Human Development
Before joining the lab, Tiffany worked as an editor, publisher, and new series developer with Arcadia Publishing.
E-mail: tiffany.frary@childrens.harvard.edu
Long H. Chu, BS - Lab Manager
Started in the Wagner Lab in July 2016
Previous Research
This is Long's first posting in a research position in a lab. Before becoming the lab manager, Long was a research assistant in the Wagner Lab.
Previous Placements
UMass Lowell, Lowell, MA, USA - BS in Molecular Biology
Eton Bioscience Inc. - Specializing in DNA Sequencing
E-mail: long.chu@childrens.harvard.edu
Started in the Wagner Lab in July 2016
Previous Research
This is Long's first posting in a research position in a lab. Before becoming the lab manager, Long was a research assistant in the Wagner Lab.
Previous Placements
UMass Lowell, Lowell, MA, USA - BS in Molecular Biology
Eton Bioscience Inc. - Specializing in DNA Sequencing
E-mail: long.chu@childrens.harvard.edu
Nicoletta Sorvillo, PhD - Post Doctoral Fellow
Started in the Wagner Lab in April 2015
Nicoletta came to the Wagner Lab from the Netherlands and Italy as a postdoctoral fellow to study the role of neutrophil extracellular traps (NETs) in the initiation and progression of thrombosis and inflammation. In particular, she is interested in the function of PAD4, the enzyme crucial for NET formation, outside the cell and determining its effect on the extracellular environment.
Previous Research
Nicoletta studied potential triggers for development of auto-antibodies in acquired thrombotic thrombocytopenic purpura (TTP). She determined the mechanism of endocytosis of ADAMTS13 by human dendritic cells and identified for the first time the repertoire of naturally MHC class II presented ADAMTS13-derived peptides. Nicoletta also analyzed the immune recognition and processing of plasma proteins, such as von Willebrand factor and Factor VIII, for the design of improved therapeutics for coagulation disorders, such as Hemophilia A.
Previous Placements
University of Naples Federico II, Naples, Italy - Masters of Medical Biotechnology
University of Amsterdam, Amsterdam, The Netherlands - PhD in Hematology and Immunology
Under the supervision of Professor Jan Voorberg at the Department of Plasma Proteins at Sanquin Research
Sanquin Research, Amsterdam, The Netherlands - Postdoctoral fellow
Under the supervision of Professor Koen Mertens and Dr. Sander Meijer with Novo Nordisk’s collaboration
E-mail: nicoletta.sorvillo@childrens.harvard.edu
Started in the Wagner Lab in April 2015
Nicoletta came to the Wagner Lab from the Netherlands and Italy as a postdoctoral fellow to study the role of neutrophil extracellular traps (NETs) in the initiation and progression of thrombosis and inflammation. In particular, she is interested in the function of PAD4, the enzyme crucial for NET formation, outside the cell and determining its effect on the extracellular environment.
Previous Research
Nicoletta studied potential triggers for development of auto-antibodies in acquired thrombotic thrombocytopenic purpura (TTP). She determined the mechanism of endocytosis of ADAMTS13 by human dendritic cells and identified for the first time the repertoire of naturally MHC class II presented ADAMTS13-derived peptides. Nicoletta also analyzed the immune recognition and processing of plasma proteins, such as von Willebrand factor and Factor VIII, for the design of improved therapeutics for coagulation disorders, such as Hemophilia A.
Previous Placements
University of Naples Federico II, Naples, Italy - Masters of Medical Biotechnology
University of Amsterdam, Amsterdam, The Netherlands - PhD in Hematology and Immunology
Under the supervision of Professor Jan Voorberg at the Department of Plasma Proteins at Sanquin Research
Sanquin Research, Amsterdam, The Netherlands - Postdoctoral fellow
Under the supervision of Professor Koen Mertens and Dr. Sander Meijer with Novo Nordisk’s collaboration
E-mail: nicoletta.sorvillo@childrens.harvard.edu
Patrick Münzer, PhD - Post Doctoral Fellow
Started in the Wagner Lab in October 2017
Previous Research
Patrick's previous work focused on the molecular basis of hemostasis and pathological thrombosis with subsequent thrombo-occlusive events leading to myocardial infarction and ischemic stroke. He investigated the role of the Phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) pathway and associated kinases in platelet signaling and activation.
Previous Placements
The University of Freiburg, Germany - BS in Biology
The University of Tübingen, Germany - PhD in Physiology
Under the supervision of Prof. Florian Lang, MD
The University Hospital of Tübingen, Germany - Postdoctoral Research Fellow in Thrombosis/Hemostasis
Under the supervision of Prof. Meinrad Gawaz, MD
E-mail: patrick.muenzer@childrens.harvard.edu
Started in the Wagner Lab in October 2017
Previous Research
Patrick's previous work focused on the molecular basis of hemostasis and pathological thrombosis with subsequent thrombo-occlusive events leading to myocardial infarction and ischemic stroke. He investigated the role of the Phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) pathway and associated kinases in platelet signaling and activation.
Previous Placements
The University of Freiburg, Germany - BS in Biology
The University of Tübingen, Germany - PhD in Physiology
Under the supervision of Prof. Florian Lang, MD
The University Hospital of Tübingen, Germany - Postdoctoral Research Fellow in Thrombosis/Hemostasis
Under the supervision of Prof. Meinrad Gawaz, MD
E-mail: patrick.muenzer@childrens.harvard.edu
Shoichi Fukui, MD, PhD - Post Doctoral Fellow
Started in the Wagner lab in June 2018
Shoichi came to the Wagner lab from Japan to study the relationship between neutrophil extracellular traps (NETs) and rheumatoid arthritis.
Previous Research
Shoichi studied subsets of monocytes and osteoclasts in rheumatoid arthritis using human peripheral blood samples. He also researched vasculitis and complement pathways clinically.
Previous Placements
Nagasaki University, Nagasaki, Japan - MD
Nagasaki University, Nagasaki, Japan - PhD in Medicine
Immunology and Rheumatology, Prof. Atsushi Kawakami
Post-doctoral Career
Assistant Professor, Department of Community Medicine, Nagasaki University, Nagasaki, Japan
E-mail: shoichi.fukui@childrens.harvard.edu
Started in the Wagner lab in June 2018
Shoichi came to the Wagner lab from Japan to study the relationship between neutrophil extracellular traps (NETs) and rheumatoid arthritis.
Previous Research
Shoichi studied subsets of monocytes and osteoclasts in rheumatoid arthritis using human peripheral blood samples. He also researched vasculitis and complement pathways clinically.
Previous Placements
Nagasaki University, Nagasaki, Japan - MD
Nagasaki University, Nagasaki, Japan - PhD in Medicine
Immunology and Rheumatology, Prof. Atsushi Kawakami
Post-doctoral Career
Assistant Professor, Department of Community Medicine, Nagasaki University, Nagasaki, Japan
E-mail: shoichi.fukui@childrens.harvard.edu
Saeko Fukui, MD - Research Assistant II
Started in the Wagner Lab in February 2019
Previous Research
This is Saeko's first posting in a research position in a lab.
Previous Placements
Nagasaki University, Nagasaki, Japan - MD
Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Medical staff in the Department of Surgery, Prof. Susumu Eguchi
E-mail: saeko.fukui@childrens.harvard.edu
Started in the Wagner Lab in February 2019
Previous Research
This is Saeko's first posting in a research position in a lab.
Previous Placements
Nagasaki University, Nagasaki, Japan - MD
Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Medical staff in the Department of Surgery, Prof. Susumu Eguchi
E-mail: saeko.fukui@childrens.harvard.edu
Sarah Gutch - Research Assistant
Started in the Wagner Lab in July 2019
Previous Research
This is Sarah's first posting in a research position in a lab.
Previous Placements
Bates College, Lewiston, ME, USA - BS in Biology
E-mail: sarah.gutch@childrens.harvard.edu
Started in the Wagner Lab in July 2019
Previous Research
This is Sarah's first posting in a research position in a lab.
Previous Placements
Bates College, Lewiston, ME, USA - BS in Biology
E-mail: sarah.gutch@childrens.harvard.edu